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“Activation of these receptors could lead to mood stabilization.” Recent research out of Israel and published in JAMA Pediatrics in late 2024 supports this theory, as nearly 7,000 adolescents with obesity who initiated a GLP-1 receptor agonist had a 33% lower risk for suicidality compared with controls who underwent behavioral interventions

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doi: 10.3389/fnins.2021.728810