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What are GLP-1 medications and how do they work Medically reviewed by Dr Sultan Linjawi, Endocrinologist & Diabetes Specialist — January 2026 GLP-1 medications have become some of the most talked-about treatments in type 2 diabetes — and for good reason

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Tirzepatide, a dual GIP/GLP-1 receptor agonist approved by the FDA for diabetes management and chronic weight management, works by enhancing insulin secretion, suppressing glucagon, and reducing appetite