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Mucinex Fast-Max and other cough and cold products contain a combination of: Acetaminophen Dextromethorphan Phenylephrine or pseudoephedrine Guaifenesin Triprolidine or other antihistamine Taking Tylenol on top of Mucinex Fast-Max can push you above the FDA’s recommended daily limit of 4,000 mg of acetaminophen, which can cause serious side effects, including: Liver damage Loss of appetite Yellowing of the skin (jaundice) Severe stomach pain Confusion or weakness People with liver problems, liver disease, or who regularly drink alcohol should be especially cautious