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Many underlying issues remain untouched, including: Hormonal imbalances Insulin resistance Chronic inflammation Poor gut health Stress-related cortisol elevation Nutrient deficiencies When the medication is stopped, the body often rebounds because the root causes were never resolved
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Thiazolidinediones (TZDs), which are peroxisome proliferator-activated receptor (PPAR)-gamma agonists, can cause dose-related fluid retention, when used in combination with insulin
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