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A positive relationship between circulating DPP-4 activity and the presence and degree of chronic hepatic conditions has been evidenced, including hepatitis C virus (HCV)-related hepatitis, nonalcoholic steatohepatitis (NASH), nonalcoholic fatty liver disease (NAFLD), and progression to cirrhosis

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PMID: 41246995 J Biol Chem Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide