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There's been a lot of discussion about GLP-1 medications and the gallbladder. At first, concerns were raised about increased risk. But newer insights suggest the relationship is more complex than we thought.
Mechanistical studies suggest that GLP-1RAs may reduce tumor growth in prostate (95) and breast cancer (96, 97)
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In skeletal muscle and adipose tissue of diabetic rats, berberine enhanced LKB1-mediated AMPK phosphorylation, which reduced TORC2 phosphorylation, suppressed PEPCK and G6Pase expression, and lowered fasting blood glucose [106,107]
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