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Possible Side Effects and What to Watch For The most common side effects are nausea, vomiting, diarrhoea, and constipation, especially during dose escalation
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This point has also been raised for beneficial effects of GLP‐1 receptor agonists in Parkinson's disease, due to a lack of expression of GLP‐1 receptors by dopaminergic substantia nigra neurons (Knudsen, 2019)