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GLP-1 Compounding Guide: FDA Updates and Conversation Tips | Critical Compounding Resources posted on the topic | LinkedIn

In HFrEF, an issue remains that because GLP-1 RAs have been shown to modestly increase heart rate (2-3 beats per minute) owing to their chronotropic effects (see “Mechanisms”) (Sun et al., 2015), GLP-1 RA treatment in HFrEF may be problematic considering that, in line with the use of beta-blockers to ameliorate HFrEF (11, 12), heart rate elevations may result in a worse outcome (DeVore et al., 2016

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There have not been any thorough accounts of how many patients are taking compounded GLP-1 meds altogether, nor are there statistics looking at how many telehealth companies are currently selling the meds, or how many compounding pharmacies are mixing GLP-1 drugs