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Tumour markers were elevated, with carbohydrate antigen 19-9 (CA 19-9) measuring 6606 kU/L
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We observed dysregulation of multiple transcription factors in the hypothalamus that are critical for various metabolic functions (Figure 4A), including impaired leptin signaling, a hallmark of BBS (24), and disrupted cholecystokinin (CCK) signaling
