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Standard-dose tirzepatide may be a good fit for patients with more significant weight loss goals, stronger food cravings, prior limited response to semaglutide, or a preference for a dual GLP-1/GIP pathway
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In the Duration 8 trial, patients with type 2 diabetes were randomized to receive exenatide (a GLP-1 receptor agonist), dapagliflozin (an SGLT2 inhibitor), or their combination
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