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The mechanisms behind addictive disorders have been extensively reviewed by several authors and comprise drug‐induced dysregulations of numerous neurocircuits and neurochemicals, such as dopamine, opioid peptides, corticotropin‐releasing factor (CRF), dynorphin, glutamate and GABA, and also vulnerability factors such as genetics, initial drug exposure and social environment (Badiani et al., 2011

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These broader outcomes reinforce the role of sustained metabolic management