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Despite the use of large-scale propensity score adjustment, 69 of 120 cohort comparisons failed study diagnostics, predominantly related to covariate imbalance and potential residual confounding, which affected all European databases
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Sleep disturbances , including obstructive sleep apnoea (which is common in individuals with obesity and type 2 diabetes), depression, anxiety, and other mental health conditions can all manifest as daytime fatigue
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