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"The effect of fatty diacid acylation of human PYY 3-36 on Y 2 receptor potency and half-life in minipigs"

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Canagliflozin was associated with a decrease in total hip bone mineral density over 104 weeks, (placebo-subtracted changes:100mg -0.9% and 300mg -1.2%), but did not result in changes in bone mineral density in the femoral neck, lumbar spine, or distal forearm (227)