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For obesity therapeutics, Phase 3 trials are especially important because regulators want to see: Long-term weight loss sustainability Cardiovascular safety Real-world tolerability Effects on obesity-related conditions such as diabetes, sleep apnea, and osteoarthritis Retatrutide’s Phase 3 program, called TRIUMPH , includes multiple large-scale studies across different patient populations

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GLP-1 and GLP-2 as yin and yang of intestinal lipoprotein production: evidence for predominance of GLP-2-stimulated postprandial lipemia in normal and insulin-resistant states