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Frontiers | Semaglutide in cognitive dysfunction: neuroprotective potential, clinical trial limitations, and a prevention-focused framework

Restarting GLP-1 therapy is a valid choice if regain impacts your health or quality of life—this reflects your individual metabolic needs, not failure

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Despite promising results in preclinical models of T2D, as well as efficacy observed in early clinical studies, the adverse event profile seen in humans, particularly elevated liver fat deposition and liver enzymes, has limited the clinical utility of glucagon receptor antagonists (152)