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Continuous flow reactors allow reaction conditions — temperature, pressure, residence time, mixing — to be controlled with precision impossible in batch stirred tanks, reducing the formation of genotoxic impurities (particularly ICH M7 Class 1 and Class 2 genotoxic impurities, which have extremely low permitted daily exposure limits)

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Iron-deficiency anemia is the most common cause of persistent fatigue in menstruating women on caloric restriction