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Furthermore, GLP-1R agonists could be administered as adjunct therapy to weight reduction in individuals with prior bariatric surgery, although a recent study suggested that LIRA did not promote the resolution of other obesity-related comorbidities (including OSA) compared to placebo in this population [115, 116]

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It is important to recognise that whilst Ozempic affects various physiological systems, its primary therapeutic targets remain glucose metabolism and appetite regulation