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In addition, neutral endopeptidase (NEP) plays a minor role in GLP-1 degradation by cleaving at six sites, Asp15-Val16, Ser18-Tyr19, Tyr19-Leu20, Glu27-Phe28, Phe28-Ile29 and Trp31-Leu32, within the central and C-terminal peptide domains [44]
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Mounjaro slows gastric emptying, which can affect how your body absorbs levothyroxine (the standard treatment for an underactive thyroid), so you’ll need to space the two medications apart during the day
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