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A study examining body composition changes 5-years post-semaglutide found those who gained weight displayed no significant changes in muscle area (188.9→198.4 cm 2 ) at the lumbar spine (L3)-level, but gained visceral (313→334 cm²), subcutaneous (449→486 cm²), and intermuscular fat (37.6→48.4 cm²), and experienced decreased muscle attenuation (13.1→5.9 HU), indicating higher muscle fat infiltration [16]
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