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In a randomised controlled trial, participants with metabolic syndrome who underwent phlebotomy had improvements in blood pressure, HbA1c and low-density lipoprotein (LDL)/high-density lipoprotein (LDL) ratio, but not in HOMA-IR [105]
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When those conditions change, the molecule can unfold, aggregate, or degrade into fragments that no longer activate your GLP-1 receptors
