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Lilly also reported 44 five-point Major Adverse Cardiovascular Event ( MACE-5 ) events — a combined clinical endpoint used to measure serious heart and blood vessel complications — among participants receiving retatrutide, compared with 52 in the placebo group, with the company noting that events occurred less frequently than anticipated in both arms
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Based on a subgroup analysis the risk was lower for PE (3.1 vs 3.9) and DVT (4.2 vs 5.0)
