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GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal. Read

The SURMOUNT-5 Trial: Head-to-Head Results SURMOUNT-5 was a 72-week, randomised, open-label Phase 3b trial that enrolled 751 adults with obesity (or overweight with at least one weight-related condition) and without diabetes

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The review is based on the published warning-letter text