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Independent readers have been discussing the side effects of GLP-1 drugs such as Ozempic and Mounjaro, with many questioning whether the risks are being fully acknowledged as use of the medications grows
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In DURATION-8 (60) the decrement in systolic blood pressure with combined exenatide/dapagliflozin therapy (4.1 mm Hg) was slightly greater than the additive effects with exenatide monotherapy (1.3 mmHg) and dapagliflozin monotherapy (1.8 mmHg), again suggesting that different mechanisms may be responsible for the two actions of the drugs
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