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And when that happens, a lot of people will see that initial weight loss in their face first." This rapid loss of facial fat can lead to sunken cheeks and temples, making the bones of the face appear more prominent.” Additionally, the skin may lose elasticity and sag, accentuating existing wrinkles and fine lines
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The objective of the study was to demonstrate that retatrutide is superior to placebo in WOMAC pain subscale score reduction and in body weight reduction from baseline to week 68 in people with a BMI ≥27.0 kg/m² and who met American College of Rheumatology Criteria (clinical and radiological) for knee osteoarthritis
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