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Figure 1.3 from Cardiovascular Effects and Mechanism(s) of Action of Glucagon-Like Peptide-1 Metabolite, GLP-1(28-36) | Semantic Scholar
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5 Market outlook Eli Lilly’s oral non-peptide GLP-1RA orforglipron is advancing through the ACHIEVE Phase III program, with Lilly signaling regulatory submissions for obesity in 2025 and type 2 diabetes in 2026, following positive results from both Phase 2 obesity (GZGI) and Phase 3 T2DM (ACHIEVE-1) trials