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95% CI, 0.38–0.99), as well as a decrease in the rate of MACE by 26% (79)
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GLP-1 receptor agonists mimic the body’s natural incretin hormone, which: Reduces appetite Slows gastric emptying Improves insulin sensitivity Supports glucose regulation Orforglipron activates GLP-1 receptors without being a peptide, allowing oral absorption without complex delivery systems