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HFpEF causes increased left ventricular mass, called LV hypertrophy.” With an increase in EAT, “the fat around the heart releases circulating adipocytokines, molecules that lead to issues like increased inflammation, fibrosis, and an increase in hypertrophy and stiffness,” notes Kramer
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Novo Nordisk has been busy scaling its manufacturing capacity to maintain meeting demand for its drugs, including $6.5bn in investments to increase production in the US in 2025
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