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[Accessed 13 August 2026] NICE Guideline NG226: Osteoarthritis in over 16s: diagnosis and management, NICE, 2022 [Accessed 13 August 2026] NICE Guideline NG28: Type 2 diabetes in adults: management, NICE, 2022 (updated) [Accessed 13 August 2026] Mounjaro (tirzepatide) 2.5mg solution for injection – Summary of Product Characteristics, Electronic Medicines Compendium (EMC), 2023 [Accessed 13 August 2026] Kolahi AA et al., Weight loss and osteoarthritis outcomes: a systematic review, BMJ, 2024 [Accessed 13 August 2026] Diabetes UK: Weight management and its impact on joint health in people with type 2 diabetes, Diabetes UK, 2023 [Accessed 13 August 2026] MHRA Drug Safety Update: Tirzepatide (Mounjaro) – new active substance approval and safety profile, MHRA, 2023 [Accessed 13 August 2026] NICE guideline NG226: Osteoarthritis in over 16s: diagnosis and management, NICE, 2022 [Accessed 13 August 2026] NICE guideline NG28: Type 2 diabetes in adults: management, NICE, 2022 (updated) [Accessed 13 August 2026] Tirzepatide monograph, British National Formulary (BNF), NICE [Accessed 13 August 2026] Mounjaro (tirzepatide) Summary of Product Characteristics, Eli Lilly, Electronic Medicines Compendium (EMC), 2023 [Accessed 13 August 2026] Jessen N et al., Weight loss and joint load reduction in knee osteoarthritis, The Lancet, 2022 [Accessed 13 August 2026] Osteoarthritis: symptoms, causes and treatment overview, Versus Arthritis, 2023 [Accessed 13 August 2026] Start Your Assessment For Weight Loss Start your journey to better health today