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“The turning point came around 2015, when higher-dose liraglutide, under the brand name Saxenda, was approved for obesity, confirming the weight loss effect wasn’t just a side effect, but a primary therapeutic action.” GLP-1s worked differently from earlier diet drugs

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Nevertheless, the type of response to GLP-1RAs and the extent of their anti-inflammatory effects may vary among different patient populations depending on the severity of the disease, the presence of comorbidities, and the characteristics of the individual patient