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However, post-market data from patient reports and smaller observational studies have documented mood-related side effects in a subset of users, suggesting that certain individuals may be more vulnerable than others
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For obesity management, NICE technology appraisal TA875 recommends semaglutide (Wegovy) only within specialist weight management services, for people with a BMI of at least 35 kg/m² (or 30 kg/m² with weight-related comorbidities) and as part of a programme including diet and physical activity for a maximum of 2 years
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