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Tirzepatide does not treat Type 1 diabetes or NAFLD, and clinical trials explore its therapeutic applications, including cardiovascular benefits for individuals with T2DM and obesity (43)

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These advancements position microneedle technology as a transformative approach for delivering GLP-1 receptor agonists, offering the potential to improve therapeutic adherence, minimize systemic side effects, and support decentralized care models for diabetes management [43]