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Las guรญas de la Asociaciรณn Americana de Diabetes (ADA) y la Asociaciรณn Europea para el estudio de la Diabetes (EASD) junto con la Sociedad Europea de Cardiologรญa recomiendan el uso de los agonistas de los receptores del GLP1 o las glifozinas como primera lรญnea de tratamiento o asociadas a metformina en los pacientes diabรฉticos tipo 2 con alto u muy alto riesgo cardiovascular y sin enfermedad cardiovascular establecida
