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If heart failure develops, evaluate and manage according to current standards of care and consider discontinuation of Sitagliptin Tablets

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In a subgroup analysis of 32,695 patients with preexisting DR, there was no association seen for GLP-1 RAs with proliferative DR or diabetic macular edema, but associations were seen with a lower occurrence of vitreous hemorrhages, neovascular glaucoma, or blindness (hazard ratios, 0.74, 0.78, and 0.77, respectively)."GLP-1 RAs may be a factor in reduced rate of vision loss leading to blindness, even among individuals with preexisting DR," the authors write