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Ro makes Super Bowl debut with Serena Williams to shift GLP-1 narrative from 'vanity' to 'vitals' | Campaign US

Mechanistically, L-tryptophan upregulated the expression of GLP-1–related genes (e.g., Gcg and Pcsk1 ) in intestinal L cells, further promoting GLP-1 production ( In contrast, some postbiotics may suppress GLP-1 signaling

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This dose results in exposures approximately 60 times the human exposure at the maximum recommended daily adult human dose (MRHD) of 100 mg/day based on AUC comparisons