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(2024) found that GLP-1 receptor agonists significantly reduced diabetic foot ulcer risk compared to insulin (HR: 0.44, 95% CI: 0.32–0.60) for short-term use and (HR: 0.74, 95% CI: 0.60–0.92) for long-term use

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Start with conservative fat grafting or non-surgical fillers if anatomy permits