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As the role of #GLP1 therapies in #MASLD continues to grow, clinicians need clear guidance. A new Practice Guidance update in #HEPATOLOGY provides evidence-based recommendations on using semaglutide therapy for MASH, including

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Factors That Affect Compounded Semaglutide Expiration Certain variables predict shorter, less reliable fridge life: Absorption into plastic Preservative absence in multi-dose containers Repeated needle punctures Temperature excursions The potency of compounded semaglutide can vary by up to 20%, according to STAT News, indicating that batch-to-batch variability is large enough to affect clinical response and complicate titration plans