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The dual GCGR/GLP‐1R agonist survodutide: Biomarkers and pharmacological profiling for clinical candidate selection - Thomas - 2024 - Diabetes, Obesity and Metabolism - Wiley Online Library

Contrave® (Bupropion + Naltrexone) How it works: Combines two medications that target areas of the brain involved in hunger and cravings

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That led them to several areas of the brain that appear to affect thirst but not appetite