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At 48 weeks, a weight reduction of ≥5%, ≥10%, and ≥15% had occurred in 100%, 93%, and 83% of those who received 12 mg of retatrutide and 27%, 9%, and 2% of those who received placebo
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GLP-1 users are recommended to eat plenty of protein, since these drugs can cause a 25-40% decrease in muscle mass over eight to 16 months, several times greater than non-medicated weight-loss approaches and age-related muscle loss
