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GLP-1 Receptor Agonists and SGLT2 Inhibitors in Type 2 Diabetes: Pleiotropic Cardiometabolic Effects and Add-on Value of a Combined Therapy | Drugs | Springer Nature Link
The GLP-1 drug class also includes Eli Lilly’s Mounjaro and Zepbound, which use the active ingredient tirzepatide, which mimics not just the hormone GLP-1 but another called GIP
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This protective effect persisted in Glp1r Tie2–/– mice, suggesting that the expression of immune cell or endothelial cell GLP-1Rs is not essential for this action
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