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In addition to the effects beyond weight loss of semaglutide on proteins related to CVD (as discussed above), other significantly regulated proteins in this analysis have previously been implicated in other conditions such as Alzheimer’s disease (TNC 58 , granulin 59,60 ), T2D (sFRP4 (refs
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ClinicalTrials.gov lists active obesity pharmacotherapy studies, including retatrutide phase 3 trials None of these are as exciting as the "stack two unproven drugs" approach
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