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“With the three together … you can actually make a single molecule, like a master key, that opens multiple doors as effectively as [individual] keys, and achieve superior outcomes.” DiMarchi knows these drugs well, having conducted pioneering research on this class of chemicals as far back as the late 1990s while employed at Eli Lilly as group vice president of research and development
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In this large real-world cohort of patients with type 2 diabetes, dual metformin and GLP-1 RA therapy was associated with a 39% lower incidence of adiposity-related cancers and a 67% lower all-cause mortality, showing a powerful combined impact on cancer prevention and survival
