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In the GLUTag cells, the previously reported lack of effect of GABA on GLP-1 release may be explained by the finding that 0.1 mm GABA did not further enhance secretion when added with 0.4 mm glycine, a normal constituent of the DMEM used as an incubation buffer in the previous experiments
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Pharmacotherapy can produce even better results when used together with more intense lifestyle interventions, especially with older generation medications (32–34)
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