glp-1 medications vs. bariatric surgery Surgery: 1- Weight Loss Surgery: 25-30% + TBWL for 10+ years GLP-1: 15-21% in trials, less in real-world 2- Metabolic Benefits: > GLP-1 3- Comorbidities: Greater resolution with Impact of gut-derived SCFAs Program:12 Week Program feed:true

glp-1 medications vs. bariatric surgery Surgery: 1- Weight Loss Surgery: 25-30% + TBWL for 10+ years GLP-1: 15-21% in trials, less in real-world 2- Metabolic Benefits: > GLP-1 3- Comorbidities: Greater resolution with Impact of gut-derived SCFAs Program:12 Week Program feed:true

Impact of gut-derived SCFAs in T2DM. SCFAs (acetate, butyrate, and... | Download Scientific Diagram

They may return to a worse body-composition phenotype: • more fat mass regained • less muscle recovered • poorer insulin sensitivity • greater metabolic fragility That could help explain why risk appears to rebound so quickly after discontinuation

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Program:12 Week Program

It’s also about how weight loss is managed