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A recent study found lots of conflicting data in the literature about just how significant this issue could be – some research suggested that up to 60 percent of total weight loss could be from lean muscle mass, while others found it was more like 15 percent
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For decades, metabolic dysfunction has been controlled using biguanide oral hypoglycemic drugs such as metformin (1,1-dimethylbiguanide hydrochloride) (62)
