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These higher retatrutide doses not only reduced liver fat, but resulted in more than 50% reductions from baseline in fasting insulin, C-peptide, and HOMA2-IR, indicating profound metabolic shifts

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In that environment of uncertainty comes a new study published last Thursday in JAMA Ophthalmology demonstrating that more than twice as many patients with diabetes exposed to GLP-1 agonists developed neovascular age-related macular degeneration (wet AMD) compared with those in a matched cohort of similar patients who were unexposed