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GIP/GLP-1 수용체 이중 작용제인 tirzepatide는 SURPASS 연구들에서 초기 2형 당뇨병 환자부터 인슐린을 사용 중인 유병기간이 긴 당뇨병 환자까지 다양한 당뇨병 환자군에서 뛰어난 혈당강하 효과와 체중감소 효과를 보여주었다