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Even though the role of GLP-1 on neuroprotection is well-known and new clinical trials have been started for its repurposing in neuroprotection, the role of GLP-1 on reward systems and its potential clinical use for reward modulation still need further studies
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administration of antisense oligonucleotides against mGPD, or a global mouse knockout, were found to lower EGP and abolish the effects of metformin on plasma glucose and EGP
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