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A GIP agonist, ZP6590 (Zealand Pharma) is currently in a phase 1 trial, and a GLP-1/GIP antagonist, maridebart cafraglutide (formerly AMG 133, Amgen) is currently in phase 2 trials
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Another study — a meta-analysis and review of 78 trials involving more than 73,000 participants — concluded that semaglutide was associated with an increased incidence of NAION but emphasized that evidence for a causal link remains inconclusive
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