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The interaction between CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) on Tregs and its ligand CD80/86 on APCs provides a negative signal for T cell activation ( 2) Production of immunoregulatory molecules
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doi: 10.1001/jama.2014.15298 [DOI] [PMC free article] [PubMed] [Google Scholar] 14
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